Actor Eric Dane has died less than one year after announcing that he had been diagnosed with ALS. He was 53.

Eric Dane rose to fame with his role as Dr. Mark Sloan on “Grey’s Anatomy.”

In April 2025, Dane announced that he had been diagnosed with ALS, also known as Lou Gehrig’s Disease. ALS is a rare degenerative disease that causes muscle paralysis. Most people live for three to five years after diagnosis.

Dane’s family announced his passing in a statement released to PEOPLE on Thursday (Feb. 19).

With heavy hearts, we share that Eric Dane passed on Thursday afternoon following a courageous battle with ALS. He spent his final days surrounded by dear friends, his devoted wife, and his two beautiful daughters, Billie and Georgia, who were the center of his world,” the statement reads. “Throughout his journey with ALS, Eric became a passionate advocate for awareness and research, determined to make a difference for others facing the same fight. He will be deeply missed and lovingly remembered always. Eric adored his fans and is forever grateful for the outpouring of love and support he’s received. The family has asked for privacy as they navigate this impossible time.”

Eric Dane married actress Rebecca Gayheart in 2004. The couple shared two daughters: Billie and Georgia.