Reba McEntire’s Daughter-in-Law Opens Up About IVF Pain “This Is the Hardest Thing We’ve Faced”
4 mins read

Reba McEntire’s Daughter-in-Law Opens Up About IVF Pain “This Is the Hardest Thing We’ve Faced”

Sometimes hope meets reality in the hardest way possible.

Marissa Blackstock, wife of Reba McEntire’s son Shelby, shared a raw update on Threads this week that proves not even the glitz and glam of country royalty can soften the blow of infertility struggles. One day into IVF, and she was already down for the count, calling the experience “awful” and reaching out for advice from anyone who’s been in the trenches before.

“Went into IVF hopeful… and day one immediately humbled me,” she wrote, detailing a whirlwind of hellish side effects that included a flared disc, night sweats so brutal she had to sleep on a towel, vomiting, hot and cold flashes, and not even being able to keep water down. “My body said: not today, sis.”

Reba McEntire's Daughter-in-Law Painful IVF ordeal - Day 1 updateReba McEntire's Daughter-in-Law Painful IVF ordeal - Day 1 update

And just like that, the filter dropped, the glamor disappeared, and what was left was the kind of honesty more women in the spotlight need to bring. This wasn’t a curated fertility influencer post. This was someone living it in real time and still trying to find the strength to get back up.

Marissa and Shelby tied the knot at Walt Disney World in 2022, but the fairytale hit real life fast. After more than two years of trying to conceive, they’re turning to IVF. And even though the science has come a long way, it’s still a brutal ride for the body and the soul. The shots, the hormones, the emotional whiplash, it’s all part of the so-called miracle.

By day six, things hadn’t gotten easier. In another update, Marissa joked that she’s now in a full-blown “situationship” with each medication. “If this were dating? Follistim is my main. Menopur’s the one I tolerate. Ganirelix? The ex that shows up uninvited,” she wrote. And the Ganirelix needle? “Blunt enough to carve wood.” Humor may be her coping mechanism, but it’s clear the toll is real.

Reba McEntire's Daughter-in-Law Painful IVF ordeal - Day 6 updateReba McEntire's Daughter-in-Law Painful IVF ordeal - Day 6 update

She’s not alone. Plenty of women filled the comments with encouragement, support, and real-world tips: switching to ice chips instead of water, grabbing break-and-shake ice packs, and preemptive stool softeners for what’s likely coming next. Small survival tricks from battle-tested veterans of the IVF world.

But there’s no shortcut through what she’s feeling. And for a family name that’s become synonymous with strength and southern grace, it’s a reminder that even steel-spined women like Marissa get knocked sideways sometimes.

Back in late 2023, Marissa praised Shelby for being her rock through it all, calling him incredibly supportive and emotionally steady even when things felt like they were spinning out. And it shows. The fact that she’s willing to speak so openly about the hardest chapter of their life together proves that this isn’t about chasing sympathy. It’s about finding solidarity.

IVF might be medical science, but the pain it causes is deeply human. And it’s more common than people like to admit. That’s what makes Marissa’s post hit so hard. No shiny announcement. Just a woman trying to hold it together through a storm that millions of others quietly weather every day.

“This. Is. Awful,” she wrote. And that’s probably the truest thing anyone has said about IVF this week.

Some folks will read that post and move on. Others will feel seen. And for Marissa, reaching out wasn’t a cry for pity. It was a call to the sisterhood of women who’ve been through it, who’ve clawed their way through hormones, heartbreak, and false hope to get to the other side.

The journey’s still just beginning for the Blackstocks, and no one knows how it’s going to end. But one thing’s clear. Marissa’s walking it with grit, grace, and a whole lot of fire.

Here’s hoping the next chapter comes with a little less pain, and maybe, just maybe, the miracle they’ve been praying for.